Adam K Wanekaya

US Patent:

20120088232, Apr 12, 2012

Filed:

Sep 30, 2011

Appl. No.:

13/250451

Inventors:

Adam Wanekaya - Springfield MO, US
Robert DeLong - Springfield MO, US
Bhaskar Datta - Springfield MO, US

Assignee:

Missouri State University - Springfield MO

International Classification:

G01N 33/53
G01N 21/64
C07H 21/00
G01N 21/49
C12Q 1/68
B82Y 15/00

US Classification:

435 61, 436501, 536 231, 422 69, 977773, 977774, 977902

Abstract:

Systems and methods are provided for detecting and quantitating one or more compounds or molecules in a sample. An aptamer-based point-of-care device (such as a strip) is described for rapid detection of target molecules such as the cancer marker p-glycoprotein (Pgp). Fluorescent molecules or gold nanoparticles may be used to detect the binding between a target molecule and the aptamer. By way of example, fluorescence resonance energy transfer (FRET) or Dynamic Light Scattering (DLS) may be used for detecting the physical and/or chemical changes caused by the binding of the aptamers to the target molecules.

US Patent:

20200080955, Mar 12, 2020

Filed:

Sep 10, 2019

Appl. No.:

16/565930

Inventors:

- Murfreesboro TN, US
Mulugeta WAYU - Murfreesboro TN, US
Ryan T. SPIDLE - Springfield MO, US
Adam WANEKAYA - Springfield MO, US

International Classification:

G01N 27/30
C07F 3/06
C01B 32/174
B82Y 40/00
B82Y 30/00
G01N 27/327

Abstract:

A zinc oxide-carbon nanotube composite is provided, the nanotube composite being selective and sensitive for detection of hydrogen peroxide, which is important for screening for early cancer detection, monitoring cardiovascular disease, detecting onset of food spoilage, and enzymatic reactions that produce hydrogen peroxide as a byproduct. Also provided are methods using said zinc oxide-carbon nanotube composite.